SetBinding sets a binding for the dependency property.
SetValue sets a value directly to the DependencyProperty (similarly AddHandler adds a handler directly to properties of type event).
These methods are exclusive when they are called for the same property. If SetBinding is called, then the values previously set using SetValue (AddHandler in events) are disregarded. The same is true the other way around: SetValue (AddHandler) resets the binding assigned with SetBinding.